European studies on cbd. Understanding cannabis has never been easier.
European studies on cbd 5 million euros are to be invested in unprecedented studies on CBD and THC. ) have recently issued several (draft) monographs for cannabis flower and cannabidiol (CBD), incorporating quality standards and testing procedures. EFSA’s NDA Panel considered the public assessment report of Epidyolex® published by the European Medicines Agency as well as peer-reviewed human studies conducted with similar preparations for its Statement on the safety of cannabidiol as a novel food: data gaps and Apr 8, 2020 · Cannabidiol (CBD) has been approved by both the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) as an add-on treatment for two rare childhood epilepsies: Dravet Syndrome Sep 23, 2021 · The current study is the first to review and combine all publicly available data suitable for public health monitoring of cannabis use in Europe. Jan 15, 2019 · However, as the role of CBD on airway remodelling and the mechanisms of CB 1 and CB 2 aren't fully elucidated, this study was designed to evaluate the effects of cannabidiol in this scenario. With the demand for CBD products on a steady incline, recent studies project that the European CBD market is going to grow by 400% over the next 5 years. It may even help PTSD sufferers. Our results indirectly advocate clearer European CBD regulations to ensure safe and high-quality products. These data indicate that topical CBD application has therapeutic potential for relief of arthritis pain-related behaviours and inflammation without evident side-effects. High-Intent Commercial Two studies gave low doses of CBD in placebo-controlled trials in patients with Crohn’s disease (20 patients, 20 mg highly puried CBD per day in olive oil, 8 weeks; Naftali et al. These studies indicated that CBD had pharmacological effects of its own, which have been investigated since then and led to the current view that CBD actually has a broad spectrum of action (2). The aim of this cross-sectional study was to gain insight into the user group of CBD, reasons for consumption Jun 7, 2022 · The European Commission has determined that cannabidiol (CBD) can be considered as a novel food (NF), and currently, 19 applications are under assessment at EFSA. Little is known about how effectively CBD works in managing chronic pain, a condition characterized by discomfort that persists beyond 3-6 months or beyond expected normal healing. These programs have also documented increases in Δ 9 -THC concentrations and Δ 9 -THC:CBD ratios in cannabis. Food Effects on the Formulation, Dosing, and Administration of Cannabidiol (CBD) in Humans: A Systematic Review of Clinical Studies Oct 18, 2022 · The European Commission (EC) has received over 150 cannabidiol (CBD) applications (ranging from chemically synthesised CBD, purified CBD extracts, and full spectrum CBD products) over the past few years. Oct 28, 2024 · Background/Objectives: Cannabis sativa L. Sep 7, 2018 · Cannabidiol (CBD), an active cannabinoid without psychotropic effects and abuse liability, has recently gained interest as a treatment option for intractable epilepsy (1). Current arthritis treatments often have side-effects attributable to active compounds as well as route of administration. PRESS RELEASE European Congress of Psychiatry 2025 CANNABIDIOL THERAPY COULD REDUCE SYMPTOMS IN AUTISTIC CHILDREN AND TEENAGERS Tuesday 8th April, 13:25 CEST - New research presented at the 2025 European Congress of Psychiatry reveals that the use of cannabidiol (CBD) cannabis extract can lead to meaningful benefits and improve the behaviour of children and adolescents with autism spectrum Oct 12, 2024 · Most of the trials reviewed are considered exploratory and do not focus on specific types of clinical anxiety or ADs as the primary condition studied. Sep 1, 2017 · Cannabidiol (CBD) is a noneuphoria producing constituent of cannabis that has the potential to relieve pain. The European Industrial Hemp Association has approved a plan for CBD and THC studies with a goal of novel food authorization. 224 mg CBD per 70 kg body weight, did neither elicit cognitive, perceptual or psychomotor effects nor Apr 14, 2025 · Cannabidiol extract may ease autism-related challenges in kids and teens, improving social responsiveness and behavior, results of a new meta-analysis suggest. Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems Epidyolex® is an orphan medicine with CBD as the active substance and is used in the treatment of rare types of epilepsy. Research on cannabidiol has gone a long way since it first started in the late 1980s. is a plant that has been used for thousands of years for its industrial and medicinal properties. Cannabidiol (CBD) attenuates inflammation and pain without side-effects, but CBD is hydrophobic and has poor oral Jun 7, 2022 · The Panel concludes that the safety of CBD as a NF cannot currently be established. Experience the same therapeutic effects as traditional cannabis, completely Farm-Bill Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa L. Sep 1, 2024 · In recent years, the increase in cannabidiol (CBD) sales in Europe has raised questions regarding the legal status of this product, as well as its safety of use. Since the production of CBD-based oils as dietary supplements has increased rapidly, and since they are frequently used for therapeutic purposes, the main scope of this study was to assess the overall quality of 14 CBD oil preparations produced in different European countries and purchased on the Internet and highlight possible criticisms. Apr 8, 2025 · New research presented at the 2025 European Congress of Psychiatry reveals that the use of cannabidiol (CBD) cannabis extract can lead to meaningful benefits and improve the behaviour of children Case studies and other relevant information is available in this database. Feb 2, 2023 · A new report offers a hopeful picture of the current and future CBD landscape in Europe. Not only that, but this study was the first of its kind that was able to get enough in-depth data to show an accurate picture of what consumers are looking for. There are uncertainties and controversies on the role and appropriate use of cannabis-b Jun 7, 2022 · The European Commission has determined that cannabidiol (CBD) can be considered as a novel food (NF), and currently, 19 applications are under assessment at EFSA. Likewise, in another small pilot study, three EB patients, who were prescribed pharmaceutical-grade sublingually administered cannabinoid-based medicine (CBM) comprising THC and CBD, reported improved pain scores, reduced pruritus and decreased overall analgesic drug intake [184]. Cannabidiol (CBD) (Figure 1) is the other cannabinoid that is found in the highest proportion with THC. Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid used in multiple sclerosis and intractable epilepsies. Discover where to buy high-quality, lab-tested CBD in Europe from trusted brands like Hempire Gardens. Primary Keywords (High Search Volume, Commercial Intent) Buy CBD flower Europe CBD hash for sale EU Best CBD flower Oct 16, 2016 · European Industrial Hemp Association (EIHA) review on: Safety and Side Effects of Cannabidiol – A review of clinical data and relevant animal studies Jan 15, 2019 · Asthma is characterized by chronic lung inflammation and airway hyperresponsiveness. Eur. , 2017) or non-insulin-fi treated type 2 diabetes (13 patients, 200 mg CBD per day for 13 weeks, twice per day in fasted state, no information on CBD source; Jadoon Oct 5, 2015 · Conclusions The results of this multicenter study on CBD treatment for intractable epilepsy in a population of children and adolescents are highly promising. However, the scientific reality is much more nuanced. Jul 28, 2020 · The aim of this study was to analyze the current regulatory frameworks of the CBD-containing products/preparations on the European market. The clinical evidence to support the use of CBD is limited to retrospective case Over the last few years, doctors have launched small-scale CBD studies and CBD clinical trials to find other potential uses for the compound. ASD affects approximately 1 in 100 children Aug 3, 2018 · Cannabis-based medicines are being approved for pain management in an increasing number of European countries. In conclusion, using CBD seems to be a promising strategy to overcome the lack of efficacy of conventional treatment for chronic pain. May 11, 2025 · Background Cannabidiol (CBD) is the primary non-psychoactive component of cannabis. Jul 31, 2025 · 🌿 "Is CBD Legal in Europe in 2025? Get the latest updates on CBD laws, THC limits, and Novel Food regulations. CBD acts in some experimental models as an anti-inflammatory, anticonvulsant, These findings demonstrate that, in a meaningful proportion of otherwise treatment-resistant patients, clinically important improvements in pain, sleep quality and SGIC of the severity of their condition are obtained with THC/CBD spray. Learn about their health benefits, legal status, and best places to buy premium CBD like Hempire Gardens. On 07 June 2022, shockwaves were sent across the industry when EFSA The European Commission has determined that cannabidiol (CBD) can be considered as a novel food (NF), and currently, 19 applications are under assessment at EFSA. Due to the recent elimination of CBD from the list of prohibited substances by federations and international institutions of sports in 2018, the use of CBD among athletes is becoming more common, making this a particularly relevant population of study (Rojas-Valverde 2021). Explore high-quality, lab-tested CBD flowers, hash, and cannabis products in Europe. In recent years, there has been a rise in the study of this plant due to its bioactive compounds for pharmaceutical applications. The use of cannabidiol (CBD) has received growing attention, and cannabis-based medicines are being explored as analgesics. Stay compliant & shop safely!" Primary Keywords (High Intent – Buyers): Buy CBD flower Europe Legal CBD flower in Germany Feb 20, 2025 · The United States Pharmacopeia (USP) and the European Pharmacopoeia (Ph. While assessing these, it has become clear that there are knowledge gaps that need to be addressed before a conclusion on the safety of CBD can be reached. The primary objective was to provide real-life observational data of clinical experience of nabiximols in contrast to formal clinical trials of effectiveness. Oct 30, 2015 · This study examined efficacy of transdermal CBD for reduction in inflammation and pain, assessing any adverse effects in a rat complete Freund's adjuvant-induced monoarthritic knee joint model. In June 2018, the first CBD-based drug, Epidiolex, was approved by the US Food and Drug Administration for Aug 29, 2022 · Ten percent of the adults in this French study used CBD, and several user profiles emerged. CBD is gaining traction in Real-world data on CBD use and safety has a crucial role alongside data from other types of studies to fill in the current gaps in our understanding. While assessing these, it has become Aug 25, 2025 · CDER researchers conducted a randomized, double-blinded, placebo-controlled study in healthy participants to evaluate the effects of daily CBD use. This Oct 18, 2025 · Explore CBD regulations across Europe in 2025 — from high-tolerance markets like Switzerland and the UK to restrictive regimes in Italy and Ireland. Patients report relief for a variety of conditions, particularly pain, without the intoxicating adverse effects of medical marijuana. Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in Cannabis, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. BACKGROUND. THC/CBD spray was well tolerated and no new safety concerns wer … Other potency monitoring programs are also present in several European countries such as The Netherlands, United Kingdom, France, and Italy. Shop legal CBD oils, gummies & flowers in Germany, UK, Switzerland & more!" Primary Keywords (High Intent – Buyers Apr 8, 2025 · For the study, researchers pooled data from three previous clinical trials looking into the use of CBD extracts to treat 276 children with autism. Aug 20, 2025 · Navigate the complex 2025 European laws for CBD, CBG, and CBN with Hempire Gardens. Jul 24, 2020 · The European Industrial Hemp Association (EIHA) is launching a large-scale project, conducted by ChemSafe, to finally establish legal and planning security for the European hemp industry and market. The results of human studies with healthy volunteers and oral treatment with pure CBD in a dose range below 300 mg CBD/day were summarized in separate tables for each of the health claims investigated. Abstract Background: Nabiximols (Sativex®), a cannabinoid-based oromucosal spray, is an add-on therapy for patients with moderate to severe multiple sclerosis spasticity (MSS) resistant to other medications. Although CBD appeared to have a faster onset and longer duration in women, more studies are required to delineate the role of biological sex. Ten percent of the adults in this French study used CBD, and several user profiles emerged. What were the limitations of the currently available data? The retrieved studies (animal studies) have been performed with non-chemically pure CBD, which could lead to confounding data (which may misrepresent or obscure the true effects of CBD). CBD is gaining notoriety as a potential treatment for a variety of mood disorders, especially generalized anxiety. Nov 14, 2023 · Discover the science behind the effects and benefits of CBD oil with our full list of cannabidiol research. Cannabidiol (CBD) is the primary non-psychoactive component of cannabis. Jun 7, 2022 · EFSA’s scientists cannot currently establish the safety of cannabidiol (CBD) as a novel food due to data gaps and uncertainties about potential hazards related to CBD intake. CBD is gaining traction in medical and biochemical research, though a comprehensive classification of CBD receptor interactions is yet to be elucidated. Discover Switzerland’s 1% THC allowance, Germany’s legalization, and trusted vendors like Hempire Gardens. Yet, legal regulations in the EU are complex and questions of potential health risks remain partly unanswered. If you have comments on any of these case studies, please send them to secretariat@cbd. CBD has a lower affinity for CB1 receptors compared to other cannabinoids like THC, and the literature indicates that CBD can still engage with CB1 receptors through allosteric modulation (Figure 2). This list is structured from high-value, high-intent keywords to more general thematic terms. This effect was particularly visible in London and Amsterdam. Their average age was 10 1/2 years old. To search the database, please select your criteria in the form below and click on the Go button. Of these, only 19 were validated and are currently under risk assessment by the European Food Safety Authority (EFSA). Apr 25, 2021 · In an experimental pain study of CBD in humans, researchers conclude that CBD pain relief is driven by both pharmacological action and psychological placebo effects. Learn about EU Novel Food status, country-specific THC limits (like Germany 0. New research presented at the 2025 European Congress of Psychiatry reveals that the use of cannabidiol (CBD)-heavy cannabis extract can lead to meaningful benefits and improve the behavior of children and adolescents with autism spectrum disorder (ASD). Consequently, EFSA has issued this statement, summarising the state of While an increasing prevalence of cannabis use disorders seem likely, the estimates of the Global Burden of Disease studies suggest the opposite. Jun 16, 2020 · The main hemp industry body in Europe has received a green light from its members to move forward with "unprecedented" studies on cannabidiol and THC as part of a joint novel food authorization application. Examination of available CBD products in North America and Europe demonstrates that CBD content can vary from none to much more than advertised and that potentially harmful other chemicals are often included. New findings reveal that CBD cannabis extract may significantly improve the behavior and emotional regulation of children Apr 4, 2024 · Chronic pain: Increasingly, human studies are substantiating the claims that CBD helps control pain. 9% of European adults aged 15 to 64 have used cannabis use in the past month – an increase of 27% against 2010 levels, which was more pronounced in older age groups. com. Cannabidiol (CBD) is known to exert immunomodulatory effects through the activation of cannabinoid-1 and − 2 (CB1 and CB 2) receptors located in the central nervous Nov 26, 2024 · Despite the existence of several studies and clinical experiences reporting therapeutic benefits using cannabis-based products, most of these studies do not yet present complete information and conclusive and extrapolable evidence on efficacy (European Monitoring Centre for Drugs and Drug Addiction, 2018; Whiting et al. 3% and France 0%), and essential import documentation to buy compliant, lab-tested cannabis products in Europe. Additionally, we focused on the evaluation of health claims while assessing the correctness of the labeling on the purchased products. Apr 9, 2025 · CBD cannabis extract may improve social responsiveness and reduce disruptive behavior in children with autism, with no increase in adverse effects, according to a recent study New findings presented at the 2025 European Congress of Psychiatry suggest that cannabidiol (CBD) cannabis extract may Aug 4, 2025 · "Wondering 'Is CBD Flower Legal in Europe?' Our 2025 Country-by-Country Guide breaks down EU laws, THC limits, and where to buy legal, lab-tested CBD flower. This study, which was presented at the 2025 European Congress of Psychiatry, could open the door to new therapeutic avenues. In Germany, little is known about people who use CBD products. The European CBD market emerged in Switzerland in 2016 and subsequently expanded across the continent. As demand for cannabidiol products surges, European countries navigate varying approaches to legality, ranging from permissive to restrictive policies. Oct 18, 2023 · Cannabidiol (CBD) attracts considerable attention for promoting good health and treating various conditions, predominantly pain, often in breach of advertising rules. What does this increase indicate about the direction of CBD research in the future? CBD in Europe: Legal Status of CBD Country by Country Alphagreen — March 12, 2021 CBD plant and capsules; image by CBDinfos. Over the next two to three years, around 3. To submit additional case studies, please click here. Serious harm is Overall, evidence regarding the therapeutic efficacy of CBD to treat anxiety is mixed, with some studies showing that CBD acutely reduces self-reported anxiety levels during a stressful task and others failing to show differences between CBD and placebo on acute anxiety responses. Nov 23, 2023 · Background Cannabidiol (CBD), a non-intoxicating substance of Cannabis sativa L. EIHA (European Industrial Hemp Association) (2018), Position Paper of the European Industrial Hemp Association on: Reasonable regulation of cannabidiol (CBD) in food, cosmetics, as herbal natural medicine and as medicinal product, EIHA, Brussels. CBD shows antiepileptic efficacy in acute and chronic seizure models in rodents but the precise mechanisms of action remain unclear (2 – 4). Understanding cannabis has never been easier. Apr 8, 2025 · Cannabidiol (CBD) may offer real relief for young people with autism, improving social interaction, reducing anxiety, and helping with sleep, all without increasing side effects. The second trend refers to an emerging market for cannabidiol (CBD) products in European countries, where regulations on CBD are lacking. Other studies showed that CBD preferentially inhibited the survival of breast cancer cells by inducing apoptosis and autophagy [65] and inhibited proliferation and cell invasion in human glioma cell lines [66]. Particularly, cannabidiol has demonstrated analgesic and non-psychoactive properties. Asthma remains a major public health problem and, at present, there are no effective interventions capable of reversing airway remodelling. Naturally, there is still much to learn about CBD. In this context, our survey assessed the use of the available CBD-containing products in Bulgaria and pharmacists’ knowledge of the phytocannabinoids. Preclinical studies show CBD has numerous cardiovascular benefits, including a reduced blood pressure (BP) response to stress. The objective of this systematic review Aug 11, 2021 · A recent European Court of Justice judgment on intra-community trade of CBD extract ruled however that CBD is not a narcotic under the UN Conventions [18], with possible implications for future regulatory approaches in areas like food and cosmetics. , is gaining consumer attention. Therefore, this systematic review aimed to synthesize evidence on the effectiveness of CBD in chronic pain management. Dec 14, 2023 · Although numerous studies have evaluated CBD products sold over the internet in previous years, this is the first Central European study. Apr 1, 2024 · Cannabidiol (CBD), a component in Cannabis, is used to treat seizures, anxiety, and pain. in 2011 on cannabidiol (CBD) safety and side effects. In addition, CBD presents several molecular and cellular mechanisms of action involved in its positive effects on chronic pain. Aug 11, 2025 · Discover why CBD hash and CBD flower are dominating Europe's wellness market in 2025. . Clinical research on CBD has included studies related to the treatment of anxiety, addiction Feb 28, 2025 · Recently, the number of registered studies in relation to CBD has increased dramatically over the past 3-4 years. Nov 7, 2025 · The European Food Safety Authority (EFSA) has once again issued a negative opinion on the use of synthetic cannabidiol (CBD) in food supplements, leading to further questions over the future of the market. Conclusion: As expected, CBD dose, route of administration, and diet were major determinants of CBD PK with oral routes providing higher bioavailability and nanotechnology formulations a faster onset. May 16, 2025 · A recent meta-analysis reaffirms the effectiveness of CBD in alleviating some symptoms associated with Autism Spectrum Disorder (ASD). Studies in which Cannabis, a combination of CBD and Δ 9 -THC, or unspecified hemp extracts were administered were not included into the assessment. While assessing these, it has become clear that there are knowledge gaps that need to As a result of the above-mentioned studies, the first plant-derived, purified, pharmaceutical-grade CBD treatment (Epidiolex ®) was approved for DS and LGS by the US Food and Drug Administration in 2018 and for the same epilepsy entities in combination with CLB by the European Medicines Agency (Epidyolex ®) in 2019. We explore how, when, and why people using products. Methods A Abstract Cannabidiol (CBD) oils are low tetrahydrocannabinol products derived from Cannabis sativa that have become very popular over the past few years. The aim of this study was to determine whether CBD is anti-nociceptive in OA, and whether inhibition of inflammation by CBD could prevent the development of OA pain and joint neuropathy. With the progressing legalization across the United States, scientists are now eager to delve deeper into the effects and benefits of CBD oil and the Explore the latest scientific research on CBD's therapeutic potential, including studies on mental health, cancer treatment, and other medical applications. 20 hours ago · Northern Europe’s cannabis revolution welcomes OilWell Cannabis, bringing Houston’s hand-crafted, top-shelf indoor exotic THCa flower, THCa Rick Simpson Oil (RSO) sublingual and vape, Delta-9 THC gummies and edibles, live rosin vapes, and THCa concentrates (wax, dabs & diamonds, and diamonds & sauce). Further prospective, well-designed clinical trials using enriched CBD medical cannabis are warranted. Cannabidiol (CBD) is a phytocannabinoid with therapeutic properties for numerous disorders exerted through molecular mechanisms that are yet to be completely identified. Having no restrictions for CBD levels below 10 mg per day can be justified because studies as early as the one by Belgrave and colleagues (1979), showed in a placebo- controlled, randomized, double-blind study that a single dose of approx. [4] It was discovered in 1940. One animal study from the European Journal of Pain suggests CBD could help lower pain and inflammation due to arthritis when applied to skin. int. In 2021, a task force, initiated by the International Association for the Study on Pain (IASP), published a series of narrative and systematic reviews and meta-analyses covering multiple aspects of pre-clinical and clinical pain research examining the efficacy and safety 3 days ago · The legal landscape surrounding CBD in Europe is rapidly evolving as 2025 unfolds, reflecting a complex interplay of regulatory frameworks, scientific research, and shifting societal attitudes. Introduction: This literature survey aims to extend the comprehensive survey performed by Bergamaschi et al. Consumption of CBD is increasing rapidly as it is federally legal and widely available in the United States, Europe, Mexico, Canada, and Asia. , 2015; Brazilian Health In this context, the investigation of the interaction between the Δ9-THC and CBD began. [16] Medically, it is an anticonvulsant used to treat two rare forms of childhood epilepsy. Participant numbers, CBD dose, treatment duration, and CBD formulation vary widely among the studies, and all but two are single-center studies. Consumers seem to be looking for solutions to various health issues. Aug 29, 2022 · Cluster analysis revealed four different CBD user profiles based on socio-demographics and behavioural characteristics. Learn about compliance, best CBD products, and future trends. Apart from updating the literature, this article focuses on clinical studies and CBD The European Cannabis Report: 8th Edition, 2023 has been compiled to provide in-depth insight into the European Cannabis market. The National Credit Union Administration (NCUA) has issued an update on hemp banking rules for credit unions. We estimate that in 2019, 3. Aug 11, 2021 · A recent European Court of Justice judgment on intra-community trade of CBD extract ruled however that CBD is not a narcotic under the UN Conventions [18], with possible implications for future regulatory approaches in areas like food and cosmetics. Clinical evidence suggests that CBD provides therapeutic benefit in Jun 1, 2019 · While an increasing prevalence of cannabis use disorders seem likely, the estimates of the Global Burden of Disease studies suggest the opposite. , has gained traction as a potential treatment for intractable chronic pain in many conditions. Mar 19, 2019 · This multicentre case-control study across ten European and one Brazilian site replicates the strong effect of daily use of high-potency cannabis on the odds for psychotic disorder in the whole sample—which, to our knowledge, is the largest to date to address this question. com, via Pixabay. Keywords: CBD therapeutic effects; neuropathic pain; nociception; pre-clinical models. Apr 8, 2025 · New research presented at the 2025 European Congress of Psychiatry reveals that the use of cannabidiol (CBD) cannabis extract can lead to meaningful benefits and improve the behavior of children The Panel concludes that the safety of CBD as a NF cannot currently be established. Those are the key findings in “The European CBD Market 2019-2020,” a research report from the European Industrial Hemp Association (EIHA) due out March 9. Cannabidiol (CBD) is a primary component in the cannabis plant; however, in recent years, interest in CBD treatments has outpaced scientific research and regulatory advancement resulting in a confusing landscape of misinformation and unsubstantiated Studies in unique populations such as elite athletes are even more sparse. Includes THC limits and Novel Food status. Mar 2, 2020 · Europe has vast potential in the CBD sector, but there’s an urgent need for legislative and regulatory reform that will unlock the market to serve the health and well-being of EU citizens. xmvyfw wylr kfwczx wdrlwdk atgwib dgdrjt ucam ithppq mcssvgwuj ldtb wjdvogp ownnu hpbluc jgkuev dne